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Feline Upper Respiratory Viruses - Part One:
Rhinotracheitis IntroductionThis is the first of two articles to explain the nature of the disease viruses that are contained within the routine upper respiratory vaccines. The purpose is to help readers understand each virus that is included: what it does, how cats get infected, what is done to treat the virus, and how to avoid or manage it. "Upper Respiratory" refers to infections in the area of the nose, throat and sinus areas. This particular virus, called Rhinotracheitis, is the most severe of all. Be aware, however, that infections from different viruses can occur at the same time in the same cat, and to differentiate which virus is causing a problem would be based on the characteristics of the disease symptoms. Rhinotracheitis is known and referred to by different names and symbols in veterinary literature, and authors assume the reader knows that they mean the same thing. It is important that readers understand what those different references are:
In this article the virus will be referred to as FVR or Rhinotracheitis. What Is Rhinotracheitis?FVR is the more severe of the two most common upper respiratory viruses, the other being Calici virus. As suggested by the name, it affects the nose ("rhino"), eyes, throat area and sinus areas. The "itis" refers to the inflammation/infection that is happening. It is referred to as an "upper" respiratory virus because it affects the area involved with breathing that is before the lungs and trachea. FVR is actually a herpes virus, specifically Herpes Virus 1, and it is specific for cats. What Does Rhinotracheitis Virus Do?A) Active Disease The virus attacks and grows in the nose, sinuses, eyes, the membranes surrounding the eyes, throat, tonsils, upper palate of the mouth and trachea. One to three days after a cat becomes infected, there are signs of severe sneezing (very important first symptom). The cat/kitten will become very depressed, run a fever, lose its appetite, and start to form a thick, mucousy discharge from the nose and possibly eyes. In some cases, the cat/kitten may drool. The lining around the inside of the eye is noticeably red and swollen. Sometimes ulcers may develop in the mouth, or the cat/kitten may develop pneumonia. These symptoms may go on for seven to 14 days, depending upon the amount of virus with which the cat/kitten was infected. (Note: The more virus that infects, the more severe the sickness produced.) If a pregnant cat becomes infected during pregnancy, the kittens may either be aborted or be born with brain or liver problems that can cause death. Cats will be very depressed with this disease, and if it is the first time they have been exposed to this virus, very ill. Kittens are more affected than adults, and up to 70% can die with severe infection. Severe infection in kittens can also cause lack of balance and seizures before death. Adults will not often die, but require much attention and nursing to make it through the disease. At some point during this infection, bacteria will also infect this same area because of all the damage the virus has caused. (This is referred to as an "opportunist" infection, as it would not normally occur if the other had not happened first.) These bacteria behave in the same fashion as the virus, and will often permanently remain to flare up time after time for the remainder of the cat's life, usually despite treatment. In the eye the damage can be great, and is a major cause of eye ulcers in cats. There is usually a decrease in tear production for the eyes as a result of this infection as well. How many of the above symptoms a cat gets, and to what degree, is dependent on a number of things, all of which are important.
B) Latent and "Carrier" Disease Eighty percent of all previously infected cats go on to become carriers of the disease. In so doing they become "latent" after recovering from the first infection. Latent is the term used for the presence of a disease organism that is not causing the disease at that particular time in that particular individual. A "carrier" cat is one who has been previously infected (and has gone through the active phase of the disease) and is now recovered. All carrier cats are either active (currently undergoing active virus infection within their bodies) or latent (the virus is present, but not active). Carrier cats in the active phase can become ill again (although not always, and usually not to the same degree as the first time) and can shed (spread virus to the environment and other cats). Cats in the latent phase only have the virus internally, but feel normal and do not shed the virus to other cats and the environment. What triggers a carrier cat to move from the latent to the active phase is STRESS. Any physical or emotional event in a cat's life can be considered stress including cat shows, moving, boarding, pregnancy, birthing, vaccinations, new family member (human or feline!), other diseases, injury, surgery, crowding, etc. An active phase, healthy looking carrier cat can shed as much virus to others and into the environment as a newly infected sick cat! One week is the usual time frame from the triggering event to the production of active, shedding virus and possible illness. It will take another two weeks for the cat to get through this active phase. Sometimes the only sign of an "active" carrier cat with Rhinotracheitis is an eye ulcer, or swollen membranes around the eye, or mild, persistent sneezing. How Do Cats Become Infected with Rhinotracheitis? All cats must come in contact with the virus to become infected. This virus makes its entrance internally through the eyes, nose or mouth.
Infected kittens become sicker and shed more virus than adult cats. Accordingly, sick kittens are the worst source of infection to other kittens, who in turn will get even sicker and shed more virus than the ones who gave it to them. The younger the kitten (under six weeks of age) the greater the reaction and resulting infection. How Is Rhinotracheitis Diagnosed?Most veterinarians will diagnose FVR based on the clinical symptoms they see. If there is a need, however, a swab can be taken from the back of the throat and sent to a specialty laboratory to positively identify the Herpes Virus 1 that causes Rhinotracheitis. Typical signs of Rhinotracheitis: Once again, lots of thick nasal discharge, swollen membranes around the eye, and depression are the most common symptoms. How Is Rhinotracheitis Treated?A cat/kitten sick with Rhinotracheitis primarily requires supportive care for the symptoms the disease produces, as it is a virus infection. Veterinarians will often prescribe antibiotics as well, because they wish to avoid the resulting bacterial infections that happen in conjunction with the damage from the virus infection. Supportive care is dependent upon the symptoms. It typically means such things as keeping the eyes and nose free of mucous, treating any eye ulcers, force feeding of fluids, and a good deal of loving care. How Can Rhinotracheitis Be Prevented?Prevention of Rhinotracheitis is a two-part program, both parts of which are equally important. Since vaccines were developed for Rhinotracheitis, the number of cats affected by this condition has dramatically decreased. It is still a disease to be reckoned with, however, because of the ease with which cats can reinfect one another, especially in multiple-cat environments. Proper immunization and management are both needed.
There is basically only one strain of Rhinotracheitis (Feline Herpes Virus-1), and immunity to it in the natural way (after infection) does not happen as is generally the case with other diseases. Reinfection can happen again as shortly as six months after an initial infection, in addition to the fact that natural infection creates carrier cats.
SummaryAlthough there is much more to the subject of vaccination and its effect on this disease, it is hoped that this discussion will increase the general understanding of Rhinotracheitis. It is important for those who have cats, especially those with groups of cats, to respect the serious consequences of this disease on the general health of felines. References:
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